Pimozide Inhibits the AcrAB-TolC Efflux Pump in Escherichia coli

Efflux pump inhibitors (EPIs) are attractive compounds to reverse multidrug-resistance in clinically relevant bacterial pathogens. In this study we tested the ability of the neuroleptic drug pimozide to inhibit the Escherichia coli AcrAB-TolC efflux pump, whose overproduction confers resistance to v...

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Detalles Bibliográficos
Autores principales: Bohnert, Jürgen A, Schuster, Sabine, Kern, Winfried V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613774/
https://www.ncbi.nlm.nih.gov/pubmed/23560030
http://dx.doi.org/10.2174/1874285801307010083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613774/
https://www.ncbi.nlm.nih.gov/pubmed/23560030
http://dx.doi.org/10.2174/1874285801307010083

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