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Pimozide Inhibits the AcrAB-TolC Efflux Pump in Escherichia coli

Efflux pump inhibitors (EPIs) are attractive compounds to reverse multidrug-resistance in clinically relevant bacterial pathogens. In this study we tested the ability of the neuroleptic drug pimozide to inhibit the Escherichia coli AcrAB-TolC efflux pump, whose overproduction confers resistance to v...

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Detalles Bibliográficos
Autores principales:	Bohnert, Jürgen A, Schuster, Sabine, Kern, Winfried V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613774/ https://www.ncbi.nlm.nih.gov/pubmed/23560030 http://dx.doi.org/10.2174/1874285801307010083

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