Mitochondrial Uncoupling and the Reprograming of Intermediary Metabolism in Leukemia Cells

Nearly 60 years ago Otto Warburg proposed, in a seminal publication, that an irreparable defect in the oxidative capacity of normal cells supported the switch to glycolysis for energy generation and the appearance of the malignant phenotype (Warburg, 1956). Curiously, this phenotype was also observe...

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Detalles Bibliográficos
Autores principales: Vélez, Juliana, Hail Jr., Numsen, Konopleva, Marina, Zeng, Zhihong, Kojima, Kensuke, Samudio, Ismael, Andreeff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613776/
https://www.ncbi.nlm.nih.gov/pubmed/23565503
http://dx.doi.org/10.3389/fonc.2013.00067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613776/
https://www.ncbi.nlm.nih.gov/pubmed/23565503
http://dx.doi.org/10.3389/fonc.2013.00067

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