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The Emerging Role of Large Immunophilin FK506 Binding Protein 51 in Cancer

FK506 binding protein 51 (FKBP51) is an immunophilin physiologically expressed in lymphocytes. Very recently, aberrant expression of this protein was found in melanoma; FKBP51 expression correlates with melanoma aggressiveness and is maximal in metastatic lesions. FKBP51 promotes NF-κB activation an...

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Detalles Bibliográficos
Autores principales: Romano, S, Sorrentino, A, Di Pace, AL, Nappo, G, Mercogliano, C, Romano, MF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613799/
https://www.ncbi.nlm.nih.gov/pubmed/22087835
http://dx.doi.org/10.2174/092986711798194333