Cargando…

The Emerging Role of Large Immunophilin FK506 Binding Protein 51 in Cancer

FK506 binding protein 51 (FKBP51) is an immunophilin physiologically expressed in lymphocytes. Very recently, aberrant expression of this protein was found in melanoma; FKBP51 expression correlates with melanoma aggressiveness and is maximal in metastatic lesions. FKBP51 promotes NF-κB activation an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Romano, S, Sorrentino, A, Di Pace, AL, Nappo, G, Mercogliano, C, Romano, MF
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613799/ https://www.ncbi.nlm.nih.gov/pubmed/22087835 http://dx.doi.org/10.2174/092986711798194333

Ejemplares similares

FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential
por: Romano, S, et al.
Publicado: (2013)

FK506-binding protein 51 is a possible novel tumoral marker
por: Romano, S, et al.
Publicado: (2010)

Structural basis of nucleic acid recognition by FK506-binding protein 25 (FKBP25), a nuclear immunophilin
por: Prakash, Ajit, et al.
Publicado: (2016)

Scaffold proteins of cancer signaling networks: The paradigm of FK506 binding protein 51 (FKBP51) supporting tumor intrinsic properties and immune escape
por: MARRONE, LAURA, et al.
Publicado: (2023)

Interactions of FK506 and Rapamycin With FK506 Binding Protein 12 in Opportunistic Human Fungal Pathogens
por: Vellanki, Sandeep, et al.
Publicado: (2020)

Circulating FK506 binding protein 51 mRNA expression in patients with pituitary adenomas
por: Yang, Yingying, et al.
Publicado: (2023)

The splicing FK506-binding protein-51 isoform plays a role in glioblastoma resistance through programmed cell death ligand-1 expression regulation
por: D’Arrigo, Paolo, et al.
Publicado: (2019)

Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52
por: Mustafi, Sourajit M., et al.
Publicado: (2014)

FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury
por: Lee, Bohm, et al.
Publicado: (2022)

Association of job stress, FK506 binding protein 51 (FKBP5) gene polymorphisms and their interaction with sleep disturbance
por: Li, Peixin, et al.
Publicado: (2023)

Transient conformations in the unliganded FK506 binding domain of FKBP51 correspond to two distinct inhibitor-bound states
por: Anderson, Janet S., et al.
Publicado: (2023)

Molecular Evolution of the Vertebrate FK506 Binding Protein 25
por: Liu, Fei, et al.
Publicado: (2014)

FK506-Binding Protein 2 Participates in Proinsulin Folding
por: Hoefner, Carolin, et al.
Publicado: (2023)

Maculopathy Associated with Tacrolimus (FK 506)
por: Koh, Taehyuk, et al.
Publicado: (2011)

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin
Publicado: (1992)

Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52
por: Zgajnar, Nadia R., et al.
Publicado: (2019)

Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain
por: Soontornniyomkij, Virawudh, et al.
Publicado: (2010)

An improved reversibly dimerizing mutant of the FK506-binding protein FKBP
por: Barrero, Juan J., et al.
Publicado: (2016)

Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35
por: Atack, Thomas C., et al.
Publicado: (2020)

Role of FK506-sensitive signals in asthmatic lung inflammation
por: Tomiaki, Chihiro, et al.
Publicado: (2022)

Role of ryanodine receptor 2 and FK506-binding protein 12.6 dissociation in pulmonary hypertension
por: Wang, Yong-Xiao, et al.
Publicado: (2023)

Analysing the visible conformational substates of the FK506-binding protein FKBP12
por: Mustafi, Sourajit M., et al.
Publicado: (2013)

FK506-binding protein 5 promotes the progression of papillary thyroid carcinoma
por: Gao, Zhenya, et al.
Publicado: (2021)

The Effect of FK 506 on the Reepithelialization of Superficial Skin Wound
por: Shin, Jeong Min, et al.
Publicado: (2017)

FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells
por: Yang, Hui, et al.
Publicado: (2015)

Abstract 23: FK506 Binding Protein Expression Within the Injured Peripheral Nerve
por: Catapano, Joseph, et al.
Publicado: (2018)

Alternative macrophage polarisation associated with resistance to anti-PD1 blockade is possibly supported by the splicing of FKBP51 immunophilin in melanoma patients
por: Troiani, Teresa, et al.
Publicado: (2020)

Analysis of FK506, timcodar (VX-853) and FKBP51 and FKBP52 chaperones in control of glucocorticoid receptor activity and phosphorylation
por: Hinds, Terry D, et al.
Publicado: (2014)

Effects of FK506 on Ca(2+) Release Channels (Review)
por: Ozawa, Terutaka
Publicado: (2008)

FK506 attenuates thymic output in patients with myasthenia gravis
por: Mitsui, Takao, et al.
Publicado: (2013)

FK506 immunosuppression for submandibular salivary gland allotransplantation in rabbit
por: Almansoori, Akram Abdo, et al.
Publicado: (2020)

49. Recruited Macrophages are Required for Neuroenhancing Effects of Fk506
por: Broberg, Curtis, et al.
Publicado: (2023)

Advancing Nerve Regeneration: Translational Perspectives of Tacrolimus (FK506)
por: Daeschler, Simeon C., et al.
Publicado: (2023)

Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6
por: Chen, Hui, et al.
Publicado: (2014)

A novel mutation in FK506 binding protein-like (FKBPL) causes male infertility
por: Akyuz Sengun, Derya, et al.
Publicado: (2021)

FK506 regulates Ca(2+) release evoked by inositol 1,4,5‐trisphosphate independently of FK‐binding protein in endothelial cells
por: Buckley, Charlotte, et al.
Publicado: (2020)

The emerging importance of immunophilins in fibrosis development
por: Alqudah, Abdelrahim, et al.
Publicado: (2022)

The role of immunophilins in viral infection()
por: Hopkins, Sam, et al.
Publicado: (2015)

FKBP51 and Cyp40 are Positive Regulators of Androgen-dependent Prostate Cancer Cell Growth and the Targets of FK506 and Cyclosporin A
por: Periyasamy, Sumudra, et al.
Publicado: (2009)

Mitochondria–Nucleus Shuttling FK506-Binding Protein 51 Interacts with TRAF Proteins and Facilitates the RIG-I-Like Receptor-Mediated Expression of Type I IFN
por: Akiyama, Taishin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fgt3hgtnaih8bvnseou6tqi9lp