miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis

p53 has attracted tremendous attention due to its master role in tumor development. Activation of p53 in tumor cells has been the prime focus for cancer drug discovery. Recent studies have shown that few miRNAs can regulate p53 activity directly or indirectly. We herein demonstrate that miR-128 posi...

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Detalles Bibliográficos
Autores principales: Adlakha, Y K, Saini, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613825/
https://www.ncbi.nlm.nih.gov/pubmed/23492773
http://dx.doi.org/10.1038/cddis.2013.46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613825/
https://www.ncbi.nlm.nih.gov/pubmed/23492773
http://dx.doi.org/10.1038/cddis.2013.46

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