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Redox homeostasis: the linchpin in stem cell self-renewal and differentiation

Stem cells are characterized by their unique ability of self-renewal to maintain the so-called stem cell pool. Over the past decades, reactive oxygen species (ROS) have been recognized as toxic aerobic metabolism byproducts that are harmful to stem cells, leading to DNA damage, senescence or cell de...

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Detalles Bibliográficos
Autores principales: Wang, Kui, Zhang, Tao, Dong, Qiang, Nice, Edouard Collins, Huang, Canhua, Wei, Yuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613828/
https://www.ncbi.nlm.nih.gov/pubmed/23492768
http://dx.doi.org/10.1038/cddis.2013.50