Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca(2+)/calmodulin signaling

TNF-related apoptosis-inducing ligand (TRAIL) is a promising cytokine for killing tumor cells. However, a number of studies have demonstrated that different cancer cells resist TRAIL treatment and, moreover, TRAIL can promote invasion and metastasis in resistant cells. Here we report that TRAIL rapi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaminskyy, V O, Surova, O V, Piskunova, T, Zborovskaya, I B, Tchevkina, E M, Andera, L, Zhivotovsky, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613829/
https://www.ncbi.nlm.nih.gov/pubmed/23470529
http://dx.doi.org/10.1038/cddis.2013.51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613829/
https://www.ncbi.nlm.nih.gov/pubmed/23470529
http://dx.doi.org/10.1038/cddis.2013.51

Ejemplares similares