Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca(2+)/calmodulin signaling

TNF-related apoptosis-inducing ligand (TRAIL) is a promising cytokine for killing tumor cells. However, a number of studies have demonstrated that different cancer cells resist TRAIL treatment and, moreover, TRAIL can promote invasion and metastasis in resistant cells. Here we report that TRAIL rapi...

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Detalles Bibliográficos
Autores principales: Kaminskyy, V O, Surova, O V, Piskunova, T, Zborovskaya, I B, Tchevkina, E M, Andera, L, Zhivotovsky, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613829/
https://www.ncbi.nlm.nih.gov/pubmed/23470529
http://dx.doi.org/10.1038/cddis.2013.51

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