Systemic isotretinoin therapy normalizes exaggerated TLR-2-mediated innate immune responses in acne patients

Retinoids are used in the treatment of inflammatory skin diseases and malignancies, but studies characterizing the in vivo actions of these drugs in humans are lacking. Isotretinoin is a pro-drug for all-trans retinoic acid that can induce long-term remissions of acne; however, its complete mechanis...

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Detalles Bibliográficos
Autores principales: Dispenza, Melanie C., Wolpert, Ellen B., Gilliland, Kathryn L., Dai, Pingqi, Cong, Zhaoyuan, Nelson, Amanda M., Thiboutot, Diane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614089/
https://www.ncbi.nlm.nih.gov/pubmed/22513780
http://dx.doi.org/10.1038/jid.2012.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614089/
https://www.ncbi.nlm.nih.gov/pubmed/22513780
http://dx.doi.org/10.1038/jid.2012.111

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