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Systemic isotretinoin therapy normalizes exaggerated TLR-2-mediated innate immune responses in acne patients
Retinoids are used in the treatment of inflammatory skin diseases and malignancies, but studies characterizing the in vivo actions of these drugs in humans are lacking. Isotretinoin is a pro-drug for all-trans retinoic acid that can induce long-term remissions of acne; however, its complete mechanis...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614089/ https://www.ncbi.nlm.nih.gov/pubmed/22513780 http://dx.doi.org/10.1038/jid.2012.111 |