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The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes

The monomer of influenza haemagglutinin is synthesized as a single polypeptide precursor that during maturation is cleaved by proteases into two active subunits. Other studies have demonstrated that the human Transmembrane Protease Serine 2 (TMPRSS2) can cleave the HA of human seasonal influenza vir...

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Detalles Bibliográficos
Autores principales: Ferrara, Francesca, Molesti, Eleonora, Böttcher-Friebertshäuser, Eva, Cattoli, Giovanni, Corti, Davide, Scott, Simon D, Temperton, Nigel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Library Publishing Media 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614188/
https://www.ncbi.nlm.nih.gov/pubmed/23577043