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A variance component based multi-marker association test using family and unrelated data
BACKGROUND: Incorporating family data in genetic association studies has become increasingly appreciated, especially for its potential value in testing rare variants. We introduce here a variance-component based association test that can test multiple common or rare variants jointly using both famil...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614458/ https://www.ncbi.nlm.nih.gov/pubmed/23497289 http://dx.doi.org/10.1186/1471-2156-14-17 |