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A variance component based multi-marker association test using family and unrelated data

BACKGROUND: Incorporating family data in genetic association studies has become increasingly appreciated, especially for its potential value in testing rare variants. We introduce here a variance-component based association test that can test multiple common or rare variants jointly using both famil...

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Detalles Bibliográficos
Autores principales: Wang, Xuefeng, Morris, Nathan J, Zhu, Xiaofeng, Elston, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614458/
https://www.ncbi.nlm.nih.gov/pubmed/23497289
http://dx.doi.org/10.1186/1471-2156-14-17