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Hunger in the Absence of Caloric Restriction Improves Cognition and Attenuates Alzheimer's Disease Pathology in a Mouse Model

It has been shown that caloric restriction (CR) delays aging and possibly delays the development of Alzheimer's disease (AD). We conjecture that the mechanism may involve interoceptive cues, rather than reduced energy intake per se. We determined that hunger alone, induced by a ghrelin agonist,...

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Detalles Bibliográficos
Autores principales: Dhurandhar, Emily J., Allison, David B., van Groen, Thomas, Kadish, Inga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614512/
https://www.ncbi.nlm.nih.gov/pubmed/23565247
http://dx.doi.org/10.1371/journal.pone.0060437