Structure Based Descriptors for the Estimation of Colloidal Interactions and Protein Aggregation Propensities

The control of protein aggregation is an important requirement in the development of bio-pharmaceutical formulations. Here a simple protein model is proposed that was used in molecular dynamics simulations to obtain a quantitative assessment of the relative contributions of proteins’ net-charges, di...

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Detalles Bibliográficos
Autores principales: Brunsteiner, Michael, Flock, Michaela, Nidetzky, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614552/
https://www.ncbi.nlm.nih.gov/pubmed/23565169
http://dx.doi.org/10.1371/journal.pone.0059797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614552/
https://www.ncbi.nlm.nih.gov/pubmed/23565169
http://dx.doi.org/10.1371/journal.pone.0059797

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