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Medial Expression of TNF-α and TNF Receptors Precedes the Development of Atherosclerotic Lesions in Apolipoprotein E/LDL Receptor Double Knockout Mice

TNF-α is present in atherosclerotic lesions, activates endothelial adhesion molecule expression, stimulates the release of proinflammatory cytokines and matrix metalloproteinases and promotes smooth muscle cell proliferation and migration. Taken together these observations suggest that TNF-α may be...

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Detalles Bibliográficos
Autores principales: Niemann-Jönsson, Audrey, Söderberg, Ingrid, Lindholm, Marie W, Jovinge, Stefan, Nilsson, Jan, Fredrikson, Gunilla Nordin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614629/
https://www.ncbi.nlm.nih.gov/pubmed/23675033