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Medial Expression of TNF-α and TNF Receptors Precedes the Development of Atherosclerotic Lesions in Apolipoprotein E/LDL Receptor Double Knockout Mice
TNF-α is present in atherosclerotic lesions, activates endothelial adhesion molecule expression, stimulates the release of proinflammatory cytokines and matrix metalloproteinases and promotes smooth muscle cell proliferation and migration. Taken together these observations suggest that TNF-α may be...
Autores principales: | Niemann-Jönsson, Audrey, Söderberg, Ingrid, Lindholm, Marie W, Jovinge, Stefan, Nilsson, Jan, Fredrikson, Gunilla Nordin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Master Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614629/ https://www.ncbi.nlm.nih.gov/pubmed/23675033 |
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