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Neutralization of IL-4 and IFN-γ Facilitates inducing TGF-β-induced CD4(+)Foxp3(+) Regulatory Cells

It has been well recognized that TGF-β is able to induce CD4(+)CD25(+)Foxp3(+) suppressor/regulatory T (iTreg) cells and IL-2 facilitates iTreg induction and expansion, however, only half of TGF-β-induced CD4(+)CD25(+) cells express Foxp3 and remaining CD4(+)CD25(+)Foxp3- cells may represent effecto...

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Detalles Bibliográficos
Autores principales: Tao, Xiaojuan, Ma, Jilin, Zhang, Yonghua, Yu, Jianning, Cai, Long, Wang, Juhua, Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614670/
https://www.ncbi.nlm.nih.gov/pubmed/23675066