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TP53 codon 72 Gene Polymorphism Paradox in Associated with Various Carcinoma Incidences, Invasiveness and Chemotherapy Responses

TP53 is the most common mutated gene in human cancers. Approximately half of all human malignancies exhibit TP53 mutations. The TP53 codon 72 polymorphism is a single-nucleotide polymorphism (SNP) in exon 4, resulting in the expression of either arginine (CGC) or proline (CCC) residues. In this arti...

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Detalles Bibliográficos
Autores principales: Lin, Hung-Yu, Huang, Chun-Hsiung, Wu, Wen-Jen, Chang, Li-Ching, Lung, For-Wey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614723/
https://www.ncbi.nlm.nih.gov/pubmed/23675098