Determination of Azelastine in Human Plasma by Validated Liquid Chromatography Coupled to Tandom Mass Spectrometry (LC-ESI/MS/MS) for the Clinical Studies

A liquid chromatography coupled to tandem mass spectrometry (LC-ESI/MS/MS) was validated to determine azelastine in human plasma. Azelastine and internal standard (IS, clomipramine) were separated using a mobile phase of acetonitrile:(5 mM)-ammonium acetate solution (70:30, v/v, pH=6.4) with flow ra...

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Detalles Bibliográficos
Autores principales: Park, Yoo-Sin, Kim, Shin-Hee, Kim, Young-Jae, Yang, Seok-Chul, Lee, Min-Ho, Shaw, Leslie M., Kang, Ju-Seop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614744/
https://www.ncbi.nlm.nih.gov/pubmed/23675185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614744/
https://www.ncbi.nlm.nih.gov/pubmed/23675185

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