Engineered FADD Induces Apoptosis via an Artificial Death-Inducing Signaling Complex (DISC)

An engineered Fas-associated death domain protein (FADD), 2DEDplusE—made previously by fusing the tandem DEDs of FADD to the E protein of lambda phage-greatly enhances apoptosis-inducing activity in adherent cells in vitro. To investigate the mechanism of apoptosis-inducing activity of this engineer...

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Detalles Bibliográficos
Autores principales: Suzuki, Emiko, Takashina, Tomoki, Nakayama, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614778/
https://www.ncbi.nlm.nih.gov/pubmed/23675143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614778/
https://www.ncbi.nlm.nih.gov/pubmed/23675143

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