Inhibition of IgE Activity to Bind its High Affinity Receptor (FcεRIα) by Mouse Anti-IgE Cε3∼4 Monoclonal Antibody (QME5)

Using computer-guided homology modeling method, the 3-D structure of the Fv fragment of a functional anti-IgE antibody (MAE11) was constructed and the spatial structure of E24-MAE11 complex was modeled based on the crystal structure of IgE-Fc (abbr. E24) and molecular docking method. Then the identi...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiao, Chun Xia, Lv, Ming, Guo, Lei Ming, Yu, Ming, Li, Yan, Lin, Zhou, Hua, Xiao Li, Hou, Chun Mei, Feng, Jian Nan, Shen, Bei Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614804/
https://www.ncbi.nlm.nih.gov/pubmed/23675156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614804/
https://www.ncbi.nlm.nih.gov/pubmed/23675156

Ejemplares similares