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Inhibition of IgE Activity to Bind its High Affinity Receptor (FcεRIα) by Mouse Anti-IgE Cε3∼4 Monoclonal Antibody (QME5)
Using computer-guided homology modeling method, the 3-D structure of the Fv fragment of a functional anti-IgE antibody (MAE11) was constructed and the spatial structure of E24-MAE11 complex was modeled based on the crystal structure of IgE-Fc (abbr. E24) and molecular docking method. Then the identi...
Autores principales: | Qiao, Chun Xia, Lv, Ming, Guo, Lei Ming, Yu, Ming, Li, Yan, Lin, Zhou, Hua, Xiao Li, Hou, Chun Mei, Feng, Jian Nan, Shen, Bei Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Master Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614804/ https://www.ncbi.nlm.nih.gov/pubmed/23675156 |
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