Mutagenic and Genotoxic Effect of Hydroxyurea

The hydroxyurea, a cytotoxic drug, is the mainly available therapeutical strategy for the treatment of sickle cell disease. This study aimed to evaluate the mutagenic and genotoxic potential of the hydroxyurea through the Salmonella/Microsome assay and micronucleus test in peripheral blood of mice....

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Detalles Bibliográficos
Autores principales: Santos, Jean L., Bosquesi, Priscila L., Almeida, Adélia E., Chin, Chung Man, Varanda, Eliana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614842/
https://www.ncbi.nlm.nih.gov/pubmed/23675245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614842/
https://www.ncbi.nlm.nih.gov/pubmed/23675245

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