Validated Densitometric TLC-Method for the Simultaneous Analysis of (R)- and (S)-Citalopram and its Related Substances Using Macrocyclic Antibiotic as a Chiral Selector: Application to the Determination of Enantiomeric Purity of Escitalopram

A novel economic procedure for the simultaneous stereospecific separation and analysis of (R)- and (S)-citalopram and its related substances or impurities has been developed and validated. Chromatography was performed on silica gel 60 F254 plates with acetonitrile: methanol: water (15:2.5:2.5: v/v/v...

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Detalles Bibliográficos
Autor principal: Soliman, Suzan Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614854/
https://www.ncbi.nlm.nih.gov/pubmed/23675256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614854/
https://www.ncbi.nlm.nih.gov/pubmed/23675256

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