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BMP2 Genetically Engineered MSCs and EPCs Promote Vascularized Bone Regeneration in Rat Critical-Sized Calvarial Bone Defects

Current clinical therapies for critical-sized bone defects (CSBDs) remain far from ideal. Previous studies have demonstrated that engineering bone tissue using mesenchymal stem cells (MSCs) is feasible. However, this approach is not effective for CSBDs due to inadequate vascularization. In our previ...

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Detalles Bibliográficos
Autores principales: He, Xiaoning, Dziak, Rosemary, Yuan, Xue, Mao, Keya, Genco, Robert, Swihart, Mark, Sarkar, Debanjan, Li, Chunyi, Wang, Changdong, Lu, Li, Andreadis, Stelios, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614944/
https://www.ncbi.nlm.nih.gov/pubmed/23565253
http://dx.doi.org/10.1371/journal.pone.0060473