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Impact of E1 and Cre on Adenovirus Vector Amplification: Developing MDCK CAV-2-E1 and E1-Cre Transcomplementing Cell Lines

Adenovirus vectors have been extensively studied through the manipulation of viral genome. However, little attention is being paid to their producer cell-lines; cells are selected according to virus yields, neglecting the expression profile of transcomplementing gene products underlying cell perform...

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Detalles Bibliográficos
Autores principales: Fernandes, Paulo, Santiago, Virgínia M., Rodrigues, Ana F., Tomás, Hélio, Kremer, Eric J., Alves, Paula M., Coroadinha, Ana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614972/
https://www.ncbi.nlm.nih.gov/pubmed/23565229
http://dx.doi.org/10.1371/journal.pone.0060342