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Hydrophobic Collapse of Trigger Factor Monomer in Solution

Trigger factor (TF) is a chaperone, found in bacterial cells and chloroplasts, that interacts with nascent polypeptide chains to suppress aggregation. While its crystal structure has been resolved, the solution structure and dynamics are largely unknown. We performed multiple molecular dynamics simu...

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Detalles Bibliográficos
Autores principales: Singhal, Kushagra, Vreede, Jocelyne, Mashaghi, Alireza, Tans, Sander J., Bolhuis, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615003/
https://www.ncbi.nlm.nih.gov/pubmed/23565160
http://dx.doi.org/10.1371/journal.pone.0059683