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Actin Polymerization Negatively Regulates p53 Function by Impairing Its Nuclear Import in Response to DNA Damage

Actin, one of the most evolutionarily conservative proteins in eukaryotes, is distributed both in the cytoplasm and the nucleus, and its dynamics plays important roles in numerous cellular processes. Previous evidence has shown that actin interacts with p53 and this interaction increases in the proc...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Wang, Min, Wang, Shuyan, Qi, Tianyang, Guo, Lijing, Li, Jinjiao, Qi, Wenjing, Ampah, Khamal Kwesi, Ba, Xueqing, Zeng, Xianlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615075/
https://www.ncbi.nlm.nih.gov/pubmed/23565200
http://dx.doi.org/10.1371/journal.pone.0060179