Increased Iron Loading Induces Bmp6 Expression in the Non-Parenchymal Cells of the Liver Independent of the BMP-Signaling Pathway

Bone morphogenetic protein 6 (BMP6) is an essential cytokine for the expression of hepcidin, an iron regulatory hormone secreted predominantly by hepatocytes. Bmp6 expression is upregulated by increased iron-levels in the liver. Both hepatocytes and non-parenchymal liver cells have detectable Bmp6 m...

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Detalles Bibliográficos
Autores principales: Enns, Caroline A., Ahmed, Riffat, Wang, Jiaohong, Ueno, Akiko, Worthen, Christal, Tsukamoto, Hidekazu, Zhang, An-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615098/
https://www.ncbi.nlm.nih.gov/pubmed/23565256
http://dx.doi.org/10.1371/journal.pone.0060534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615098/
https://www.ncbi.nlm.nih.gov/pubmed/23565256
http://dx.doi.org/10.1371/journal.pone.0060534

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