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The Drosophila Over Compensating Males Gene Genetically Inhibits Dosage Compensation in Males
Male Drosophila are monosomic for the X chromosome, but survive due to dosage compensation. They use the Male Specific Lethal (MSL) complex composed of noncoding roX RNA and histone modifying enzymes to hypertranscribe most genes along the X ∼1.6–1.8 fold relative to each female allele. It is not kn...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615101/ https://www.ncbi.nlm.nih.gov/pubmed/23565249 http://dx.doi.org/10.1371/journal.pone.0060450 |