Cargando…

MEK inhibitors as a chemotherapeutic intervention in multiple myeloma

The Ras/Raf/MEK/extracellular signal regulated kinase (ERK) (Ras/mitogen-activated protein kinases (MAPK)) signal transduction pathway is a crucial mediator of many fundamental biological processes, including cellular proliferation, survival, angiogenesis and migration. Aberrant signalling through t...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang-Yew Leow, C, Gerondakis, S, Spencer, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615214/
https://www.ncbi.nlm.nih.gov/pubmed/23524590
http://dx.doi.org/10.1038/bcj.2013.1