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Mathematical Modeling of Cancer Invasion: The Role of Membrane-Bound Matrix Metalloproteinases

One of the hallmarks of cancer growth and metastatic spread is the process of local invasion of the surrounding tissue. Cancer cells achieve protease-dependent invasion by the secretion of enzymes involved in proteolysis. These overly expressed proteolytic enzymes then proceed to degrade the host ti...

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Detalles Bibliográficos
Autores principales: Deakin, Niall E., Chaplain, Mark A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615222/
https://www.ncbi.nlm.nih.gov/pubmed/23565505
http://dx.doi.org/10.3389/fonc.2013.00070