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Enhanced levels of the apoptotic BAX/BCL-2 ratio in children with acute lymphoblastic leukemia and high-risk features

It has been suggested that leukemia is characterized by an impaired balance between the proliferation of blood cells and their capacity to undergo apoptosis. The aim of this study was to examine the expression of key molecules related to apoptosis (BCL-2, BAX, FAS, FAS-L) in children with acute lymp...

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Detalles Bibliográficos
Autores principales: Kaparou, Maria, Choumerianou, Despoina, Perdikogianni, Chrysoula, Martimianaki, Georgia, Kalmanti, Maria, Stiakaki, Eftichia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615527/
https://www.ncbi.nlm.nih.gov/pubmed/23569402
http://dx.doi.org/10.1590/S1415-47572013005000003