Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells

As inhibitor of apoptosis (IAP) proteins can regulate additional signaling pathways beyond apoptosis, we investigated the effect of the second mitochondrial activator of caspases (Smac) mimetic BV6, which antagonizes IAP proteins, on non-apoptotic functions in glioblastoma (GBM). Here, we identify n...

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Detalles Bibliográficos
Autores principales: Tchoghandjian, A, Jennewein, C, Eckhardt, I, Rajalingam, K, Fulda, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615728/
https://www.ncbi.nlm.nih.gov/pubmed/23538445
http://dx.doi.org/10.1038/cddis.2013.70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615728/
https://www.ncbi.nlm.nih.gov/pubmed/23538445
http://dx.doi.org/10.1038/cddis.2013.70

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