Ophiobolin A induces paraptosis-like cell death in human glioblastoma cells by decreasing BKCa channel activity

Glioblastoma multiforme (GBM) is the most lethal and common malignant human brain tumor. The intrinsic resistance of highly invasive GBM cells to radiation- and chemotherapy-induced apoptosis accounts for the generally dismal treatment outcomes. This study investigated ophiobolin A (OP-A), a fungal...

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Detalles Bibliográficos
Autores principales: Bury, M, Girault, A, Mégalizzi, V, Spiegl-Kreinecker, S, Mathieu, V, Berger, W, Evidente, A, Kornienko, A, Gailly, P, Vandier, C, Kiss, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615734/
https://www.ncbi.nlm.nih.gov/pubmed/23538442
http://dx.doi.org/10.1038/cddis.2013.85

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615734/
https://www.ncbi.nlm.nih.gov/pubmed/23538442
http://dx.doi.org/10.1038/cddis.2013.85

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