The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner

Ras association (RalGDS/AF-6) domain family member RASSF5 is a non-enzymatic RAS effector super family protein, known to be involved in cell growth regulation. Expression of RASSF5 is found to be extinguished by promoter hypermethylation in different human cancers, and its ectopic expression suppres...

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Detalles Bibliográficos
Autores principales: Suryaraja, R, Anitha, M, Anbarasu, K, Kumari, G, Mahalingam, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615736/
https://www.ncbi.nlm.nih.gov/pubmed/23538446
http://dx.doi.org/10.1038/cddis.2013.91

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615736/
https://www.ncbi.nlm.nih.gov/pubmed/23538446
http://dx.doi.org/10.1038/cddis.2013.91

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