Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin α6β4-dependent Akt, GSK-3β, and HSF-1 in mesenchymal stem cells

Netrin (Ntn) has the potential to be successfully applied as an anti-apoptotic agent with a high affinity for tissue, for therapeutic strategies of umbilical cord blood-derived mesenchymal stem cells (UCB-MSC), although the mechanism by which Ntn-1 protects hypoxic injury has yet to be identified. T...

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Detalles Bibliográficos
Autores principales: Son, T W, Yun, S P, Yong, M S, Seo, B N, Ryu, J M, Youn, H Y, Oh, Y M, Han, H J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615739/
https://www.ncbi.nlm.nih.gov/pubmed/23538444
http://dx.doi.org/10.1038/cddis.2013.94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615739/
https://www.ncbi.nlm.nih.gov/pubmed/23538444
http://dx.doi.org/10.1038/cddis.2013.94

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