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Cadmium induced Drp1-dependent mitochondrial fragmentation by disturbing calcium homeostasis in its hepatotoxicity

Mitochondria are critical targets in the hepatotoxicity of cadmium (Cd). Abnormal mitochondrial dynamics have been increasingly implicated in mitochondrial dysfunction in pathophysiological conditions. Therefore, our study aimed to investigate the effects and underlying mechanism of Cd on mitochondr...

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Detalles Bibliográficos
Autores principales: Xu, S, Pi, H, Chen, Y, Zhang, N, Guo, P, Lu, Y, He, M, Xie, J, Zhong, M, Zhang, Y, Yu, Z, Zhou, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615741/
https://www.ncbi.nlm.nih.gov/pubmed/23492771
http://dx.doi.org/10.1038/cddis.2013.7