Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells

We reported that the class I HDAC inhibitor entinostat induced apoptosis in erbB2-overexpressing breast cancer cells via downregulation of erbB2 and erbB3. Here, we study the molecular mechanism by which entinostat dual-targets erbB2/erbB3. Treatment with entinostat had no effect on erbB2/erbB3 mRNA...

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Detalles Bibliográficos
Autores principales: Wang, S, Huang, J, Lyu, H, Lee, C-K, Tan, J, Wang, J, Liu, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615747/
https://www.ncbi.nlm.nih.gov/pubmed/23519125
http://dx.doi.org/10.1038/cddis.2013.79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615747/
https://www.ncbi.nlm.nih.gov/pubmed/23519125
http://dx.doi.org/10.1038/cddis.2013.79

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