Cargando…

Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells

We reported that the class I HDAC inhibitor entinostat induced apoptosis in erbB2-overexpressing breast cancer cells via downregulation of erbB2 and erbB3. Here, we study the molecular mechanism by which entinostat dual-targets erbB2/erbB3. Treatment with entinostat had no effect on erbB2/erbB3 mRNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, S, Huang, J, Lyu, H, Lee, C-K, Tan, J, Wang, J, Liu, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615747/ https://www.ncbi.nlm.nih.gov/pubmed/23519125 http://dx.doi.org/10.1038/cddis.2013.79

Ejemplares similares

MiR-193b, downregulated in Ewing Sarcoma, targets the ErbB4 oncogene to inhibit anchorage-independent growth
por: Moore, Colin, et al.
Publicado: (2017)

miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance
por: De Cola, A, et al.
Publicado: (2015)

Downregulation of intratumoral expression of miR-205, miR-200c and miR-125b in primary human cutaneous melanomas predicts shorter survival
por: Sánchez-Sendra, Beatriz, et al.
Publicado: (2018)

miR-125b acts as a tumor suppressor in chondrosarcoma cells by the sensitization to doxorubicin through direct targeting the ErbB2-regulated glucose metabolism
por: Tang, Xian-ye, et al.
Publicado: (2016)

Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway
por: Horie, Takahiro, et al.
Publicado: (2010)

miR-148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer
por: Zhao, Wei, et al.
Publicado: (2019)

MiR-323a regulates ErbB3/EGFR and blocks gefitinib resistance acquisition in colorectal cancer
por: Zhang, Yuanzhou, et al.
Publicado: (2022)

SNP rs3202538 in 3′UTR region of ErbB3 regulated by miR-204 and miR-211 promote gastric cancer development in Chinese population
por: Shi, Yaxiang, et al.
Publicado: (2017)

The Prognostic Value of miR-125b, miR-200c and miR-205 in Primary Cutaneous Malignant Melanoma Is Independent of BRAF Mutational Status
por: Sánchez-Sendra, Beatriz, et al.
Publicado: (2022)

Novel microRNA, miR-sc6, modulates Schwann cell phenotype via targeting ErbB4
por: Chen, Chu, et al.
Publicado: (2019)

Hyperleptinemia in obese state renders luminal breast cancers refractory to tamoxifen by coordinating a crosstalk between Med1, miR205 and ErbB
por: Nagalingam, Arumugam, et al.
Publicado: (2021)

miR372 Promotes Progression of Liver Cancer Cells by Upregulating erbB-2 through Enhancement of YB-1
por: Lin, Zhuojia, et al.
Publicado: (2018)

Clinical Significance of MiR-130b and MiR-125b as Biomarkers in Hepatocellular Carcinoma
por: El-Naidany, Sherin Sobhy, et al.
Publicado: (2022)

The Emerging Roles of miR-125b in Cancers
por: Wang, Ying, et al.
Publicado: (2020)

Overexpression of miR125b Promotes Osteoporosis Through miR-125b-TRAF6 Pathway in Postmenopausal Ovariectomized Rats
por: Wang, Gang, et al.
Publicado: (2021)

The regulation roles of miR-125b, miR-221 and miR-27b in porcine Salmonella infection signalling pathway
por: Yao, Min, et al.
Publicado: (2016)

Plasma miR‐125a and miR‐125b in sepsis: Correlation with disease risk, inflammation, severity, and prognosis
por: Zhao, Danna, et al.
Publicado: (2020)

Expression levels of plasma exosomal miR-124, miR-125b, miR-133b, miR-130a and miR-125b-1-3p in severe asthma patients and normal individuals with emphasis on inflammatory factors
por: Atashbasteh, Mostafa, et al.
Publicado: (2021)

Roles and Mechanism of miR-199a and miR-125b in Tumor Angiogenesis
por: He, Jun, et al.
Publicado: (2013)

Modulation of ErbB2 Blockade in ErbB2-Positive Cancers: The Role of ErbB2 Mutations and PHLDA1
por: Li, Guangyuan, et al.
Publicado: (2014)

LncRNA EGOT/miR-211-5p Affected Radiosensitivity of Rectal Cancer by Competitively Regulating ErbB4
por: Li, Chunxiang, et al.
Publicado: (2021)

Essential functions of miR‐125b in cancer
por: Peng, Boya, et al.
Publicado: (2020)

Hypermethylation-Associated Silencing of miR-125a and miR-125b: A Potential Marker in Colorectal Cancer
por: Chen, Hui, et al.
Publicado: (2015)

Function and regulation of miR-186-5p, miR-125b-5p and miR-1260a in chordoma
por: Huo, Xulei, et al.
Publicado: (2023)

MicroRNA miR-100 Decreases Glioblastoma Growth by Targeting SMARCA5 and ErbB3 in Tumor-Initiating Cells
por: Alrfaei, Bahauddeen M., et al.
Publicado: (2020)

miR-125b and miR-100 Are Predictive Biomarkers of Response to Induction Chemotherapy in Osteosarcoma
por: Kubota, Daisuke, et al.
Publicado: (2016)

rs12976445 variant in the pri-miR-125a correlates with a lower level of hsa-miR-125a and ERBB2 overexpression in breast cancer patients
por: LEHMANN, TOMASZ P., et al.
Publicado: (2013)

FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion
por: Benlimame, Naciba, et al.
Publicado: (2005)

Dysregulated miR-155 and miR-125b Are Related to Impaired B-cell Responses in Down Syndrome
por: Farroni, Chiara, et al.
Publicado: (2018)

miR-20b and miR-125a promote tumorigenesis in radioresistant esophageal carcinoma cells
por: Chen, Didi, et al.
Publicado: (2021)

Peripheral blood mononuclear cells expression of miR-200c, miR-125b, miR-27b, miR-203, and miR-155 in patients with significant or insignificant coronary artery stenosis
por: Saadatian, Zahra, et al.
Publicado: (2023)

Evaluation of miR-let-7f, miR-125a, and miR-125b expression levels in sputum and serum samples of Iranians and Afghans with pulmonary tuberculosis
por: Nour Neamatollahi, Ali, et al.
Publicado: (2023)

miR-302b is a potential molecular marker of esophageal squamous cell carcinoma and functions as a tumor suppressor by targeting ErbB4
por: Zhang, Mingxin, et al.
Publicado: (2014)

miR-34a and miR-125b Expression in HPV Infection and Cervical Cancer Development
por: Ribeiro, Joana, et al.
Publicado: (2015)

MiR-146 and miR-125 in the regulation of innate immunity and inflammation
por: Lee, Hye-Mi, et al.
Publicado: (2016)

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b
por: Vergani, Elisabetta, et al.
Publicado: (2015)

miR-125b and miR-223 Contribute to Inflammation by Targeting the Key Molecules of NFκB Pathway
por: Valmiki, Swati, et al.
Publicado: (2020)

A monoclonal antibody targeting ErbB2 domain III inhibits ErbB2 signaling and suppresses the growth of ErbB2-overexpressing breast tumors
por: Meng, Y, et al.
Publicado: (2016)

MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients
por: Jesionek-Kupnicka, Dorota, et al.
Publicado: (2017)

Expression of oncogenes in thyroid tumours: coexpression of c-erbB2/neu and c-erbB.
por: Aasland, R., et al.
Publicado: (1988)

Cannot write session to /tmp/vufind_sessions/sess_fb2ile5577tcbq2p1g2im3vpku