Voltage Preconditioning Allows Modulated Gene Expression in Neurons Using PEI-complexed siRNA

We present here a high efficiency, high viability siRNA-delivery method using a voltage-controlled chemical transfection strategy to achieve modulated delivery of polyethylenimine (PEI) complexed with siRNA in an in vitro culture of neuro2A cells and neurons. Low voltage pulses were applied to adher...

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Detalles Bibliográficos
Autores principales: Sridharan, Arati, Patel, Chetan, Muthuswamy, Jit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615821/
https://www.ncbi.nlm.nih.gov/pubmed/23531602
http://dx.doi.org/10.1038/mtna.2013.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615821/
https://www.ncbi.nlm.nih.gov/pubmed/23531602
http://dx.doi.org/10.1038/mtna.2013.10

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