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Voltage Preconditioning Allows Modulated Gene Expression in Neurons Using PEI-complexed siRNA
We present here a high efficiency, high viability siRNA-delivery method using a voltage-controlled chemical transfection strategy to achieve modulated delivery of polyethylenimine (PEI) complexed with siRNA in an in vitro culture of neuro2A cells and neurons. Low voltage pulses were applied to adher...
Autores principales: | Sridharan, Arati, Patel, Chetan, Muthuswamy, Jit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615821/ https://www.ncbi.nlm.nih.gov/pubmed/23531602 http://dx.doi.org/10.1038/mtna.2013.10 |
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