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Physicochemical characterization and aerosol dispersion performance of organic solution advanced spray-dried cyclosporine A multifunctional particles for dry powder inhalation aerosol delivery

In this systematic and comprehensive study, inhalation powders of the polypeptide immunosuppressant drug – cyclosporine A – for lung delivery as dry powder inhalers (DPIs) were successfully designed, developed, and optimized. Several spray drying pump rates were rationally chosen. Comprehensive phys...

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Detalles Bibliográficos
Autores principales: Wu, Xiao, Zhang, Weifen, Hayes, Don, Mansour, Heidi M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615928/
https://www.ncbi.nlm.nih.gov/pubmed/23569375
http://dx.doi.org/10.2147/IJN.S40904