Clinical implication of centrosome amplification and expression of centrosomal functional genes in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a low proliferative tumor of postgerminal center plasma cell (PC). Centrosome amplification (CA) is supposed to be one of the mechanisms leading to chromosomal instability. Also, CA is associated with deregulation of cell cycle, mitosis, DNA repair and proliferat...

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Detalles Bibliográficos
Autores principales: Dementyeva, Elena, Kryukov, Fedor, Kubiczkova, Lenka, Nemec, Pavel, Sevcikova, Sabina, Ihnatova, Ivana, Jarkovsky, Jiri, Minarik, Jiri, Stefanikova, Zdena, Kuglik, Petr, Hajek, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615957/
https://www.ncbi.nlm.nih.gov/pubmed/23522059
http://dx.doi.org/10.1186/1479-5876-11-77

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615957/
https://www.ncbi.nlm.nih.gov/pubmed/23522059
http://dx.doi.org/10.1186/1479-5876-11-77

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