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Genomic and Structural Characterization of Kunitz-Type Peptide LmKTT-1a Highlights Diversity and Evolution of Scorpion Potassium Channel Toxins

BACKGROUND: Recently, a new subfamily of long-chain toxins with a Kunitz-type fold was found in scorpion venom glands. Functionally, these toxins inhibit protease activity and block potassium channels. However, the genomic organization and three-dimensional (3-D) structure of this kind of scorpion t...

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Detalles Bibliográficos
Autores principales: Chen, Zongyun, Luo, Fan, Feng, Jing, Yang, Weishan, Zeng, Danyun, Zhao, Ruiming, Cao, Zhijian, Liu, Maili, Li, Wenxin, Jiang, Ling, Wu, Yingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616063/
https://www.ncbi.nlm.nih.gov/pubmed/23573241
http://dx.doi.org/10.1371/journal.pone.0060201