Interference in DNA Replication Can Cause Mitotic Chromosomal Breakage Unassociated with Double-Strand Breaks

Morphological analysis of mitotic chromosomes is used to detect mutagenic chemical compounds and to estimate the dose of ionizing radiation to be administered. It has long been believed that chromosomal breaks are always associated with double-strand breaks (DSBs). We here provide compelling evidenc...

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Detalles Bibliográficos
Autores principales: Fujita, Mari, Sasanuma, Hiroyuki, Yamamoto, Kimiyo N., Harada, Hiroshi, Kurosawa, Aya, Adachi, Noritaka, Omura, Masato, Hiraoka, Masahiro, Takeda, Shunichi, Hirota, Kouji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616066/
https://www.ncbi.nlm.nih.gov/pubmed/23573231
http://dx.doi.org/10.1371/journal.pone.0060043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616066/
https://www.ncbi.nlm.nih.gov/pubmed/23573231
http://dx.doi.org/10.1371/journal.pone.0060043

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