Engineering Agatoxin, a Cystine-Knot Peptide from Spider Venom, as a Molecular Probe for In Vivo Tumor Imaging

BACKGROUND: Cystine-knot miniproteins, also known as knottins, have shown great potential as molecular scaffolds for the development of targeted therapeutics and diagnostic agents. For this purpose, previous protein engineering efforts have focused on knottins based on the Ecballium elaterium trypsi...

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Detalles Bibliográficos
Autores principales: Moore, Sarah J., Leung, Cheuk Lun, Norton, Heidi K., Cochran, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616073/
https://www.ncbi.nlm.nih.gov/pubmed/23573262
http://dx.doi.org/10.1371/journal.pone.0060498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616073/
https://www.ncbi.nlm.nih.gov/pubmed/23573262
http://dx.doi.org/10.1371/journal.pone.0060498

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