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Coumadin-induced skin necrosis in a 64 year-old female despite LMWH bridging therapy

BACKGROUND: Coumadin is the standard oral anticoagulant used in a variety of clinical conditions. Coumadin inhibits the vitamin-K dependent gamma-carboxylation of coagulation factors II, VII, IX, X and the anticoagulant proteins C and S. Rarely, skin necrosis occurs when the resultant initial procoa...

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Detalles Bibliográficos
Autores principales: Kumar, Mehandar, Abrina, Vanessa Mae, Chittimireddy, Sasikala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616170/
https://www.ncbi.nlm.nih.gov/pubmed/23569516
http://dx.doi.org/10.12659/AJCR.883247