Rapamycin extends life span of Rb1(+/−) mice by inhibiting neuroendocrine tumors

Chronic treatment of mice with an enterically released formulation of rapamycin (eRapa) extends median and maximum life span, partly by attenuating cancer. The mechanistic basis of this response is not known. To gain a better understanding of these in vivo effects, we used a defined preclinical mode...

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Detalles Bibliográficos
Autores principales: Livi, Carolina B., Hardman, Rulon L., Christy, Barbara A., Dodds, Sherry G., Jones, Diane, Williams, Charnae, Strong, Randy, Bokov, Alex, Javors, Martin A., Ikeno, Yuji, Hubbard, Gene, Hasty, Paul, Sharp, Zelton Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616197/
https://www.ncbi.nlm.nih.gov/pubmed/23454836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616197/
https://www.ncbi.nlm.nih.gov/pubmed/23454836

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